Monoclonal Antibodies to Soluble Human MD-2

Tech ID: 19253 / UC Case 2003-058-0

Technology Description

MD-2 is an adapter protein of an innate immunity receptor, toll-like receptor 4. Thirteen hybridoma cell lines have been generated that produce mAbs specific to soluble human MD-2. These Abs have been characterized and have applications in immunological assays and functional studies. Some of the mAbs cross-react with mouse MD-2.

Related Materials: Viriyakosol, S., Tobias, P.S., Kitchens, R.L. and Kirkland., T.N. (2001) J.Biol.Chem. 276: 38044-38051

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Inventors

  • Kirkland, Theo N.

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